Mohamad-Ali Salloum is a Pharmacist and science writer. He loves simplifying science to the general public and healthcare students through words and illustrations. When he's not working, you can usually find him in the gym, reading a book, or learning a new skill.
Sleep: The Secret Performance Drug You're Probably Not Using Enough
Mohamad-Ali Salloum, PharmD • February 1, 2026
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Most people think of sleep as “rest.”
Athletes and high‑performers should think of it as legal doping, brain fuel, and a built‑in repair workshop
happening every night.
Let’s explore how sleep shapes both your brain and your body, with real data from top‑tier journals like SLEEP , British Journal of Sports Medicine , Sports Medicine – Open , Cell , Frontiers, Springer Nature and more.
🧠 Part 1 — Sleep and Your Brain: Why a Tired Mind Behaves Like a Slow Computer
🔍 1. Sleep loss shrinks your attention span
Research from Nature Portfolio shows that even one short night of sleep can noticeably impair sustained attention, making reaction times slower and mental mistakes more common (think: missing an exit on the highway or zoning out during a meeting). nature.com
Scientists measure this using something called the PVT (Psychomotor Vigilance Test) — a fancy name for tapping a button when a light flashes. After bad sleep, people react slower and miss more signals. nature.com
In simple terms:
Your brain becomes the Wi‑Fi signal in a crowded café — laggy and unreliable.
Your brain becomes the Wi‑Fi signal in a crowded café — laggy and unreliable.
🧩 2. Executive function — your “mental CEO” — stops leading
A 2023 review found that poor sleep disrupts executive function: planning, decision‑making, resisting impulses, and switching focus. link.springer.com
Ever sent an email you regretted? Forgot an obvious detail?
That’s what happens when your “mental CEO” shows up tired.
📚 3. Memory actually needs sleep to work properly
A long-term study following adults for 7–9 years discovered that better sleep efficiency predicted better memory performance years later. frontiersin.org
Your brain literally stores memories at night — like “ saving progress ” in a video game.
🧼 4. Your brain cleans itself at night
Yes, really.
During deep sleep, the glymphatic system(your brain's built‑in cleaning crew) washes away metabolic waste like amyloid‑β — a protein linked to Alzheimer's. Modern studies show that slow, rhythmic pulses of cerebrospinal fluid during NREM sleep are what power this cleaning operation. link.springer.com , cell.com
Think of deep sleep as a nightly dishwasher cycle
for your brain.
Skip it, and yesterday's “dirty dishes” pile up.
🏃♂️ Part 2 — Sleep and Athletic Performance: Your Hidden Superpower
Sleep doesn’t just boost your brain — it supercharges your muscles, reaction time, endurance, accuracy, mood, and recovery.
🥵 1. Sleep loss kills performance across the board
A large 2025 meta‑analysis found sleep deprivation significantly reduces:
- Endurance
- Speed
- Strength
- Explosive power
- Skill accuracy
And increases fatigue frontiersin.org
These are not small dips — many effects reach moderate to large impairments.
🥇 2. Sleep more → Perform better (the Stanford basketball study)
One of the most famous athlete‑sleep studies showed that after several weeks of sleep extension(aiming for 10 hours in bed):
- Sprint time improved
- Free‑throw accuracy jumped 9%
- 3‑point accuracy improved 9.2%
- Reaction time improved psycnet.apa.org
If sleep were a supplement, athletes would pay hundreds for these results.
🚴 3. One bad night hurts next‑day training
A 2023 cycling study showed that sleeping only ~3 hours between training sessions reduced peak power and 20‑min time‑trial performance the next morning. onlinelibr….wiley.com
You can feel this one in your soul — it’s the “ my legs just aren’t there today ” phenomenon.
😴 4. Naps are performance enhancers
A 2022–2023 series of randomized controlled trials show:
- 30–60 min naps improve cognitive performance, power output, and reduce fatigue
- Naps <1 hour significantly increased peak power in elite rugby players (+158 W!) bjsm.bmj.com , academic.oup.com
Takeaway: Nap guilt is cancelled.
✈️ 5. Travel, jet lag & competition = sleep disaster
Systematic reviews show:
- Athletes sleep less during training camps and competitions
- Early-morning training and night competitions reduce sleep duration
- Jet lag can take 1 day per time zone (eastward) or 0.5 days per zone (westward) to recover bjsm.bmj.com , bjsm.bmj.com
If you’ve ever raced or played after flying east — you KNOW.
🤕 Part 3 — Sleep & Injury Risk: The Hidden Cost
Poor sleep isn’t just about low energy — it raises injury risk.
Athletes sleeping <7 hours have significantly higher musculoskeletal injury rates.
Meta‑analytic findings suggest ~1.3–1.7× increased risk for those sleeping less. bjsm.bmj.com
Why?
Because poor sleep reduces reaction speed + increases fatigue + slows tissue repair.
A perfect storm for rolled ankles, pulled muscles, and sloppy landings.
🛠️ Part 4 — How to Use Sleep as a Performance Tool
Here’s your evidence‑based, athlete‑friendly sleep plan.
✔️ 1. Aim for ≥7 hours (non-negotiable minimum)
This is the consensus from sleep medicine authorities. aasm.org
Athletes often benefit from 8–10 hours, especially during heavy training.
✔️ 2. Improve sleep quality
Poor sleep efficiency predicts worse executive function and memory.
Ways to fix it: link.springer.com
- Same sleep & wake time daily
- Dim lights 60–90 min before bed
- Cool, dark, quiet bedroom
- Avoid late caffeine
✔️ 3. Use naps as strategic ammo
Evidence-backed nap guidelines:
- 30–60 minutes
- Best between 13:00–16:00
- Leave 60+ minutes before training to avoid grogginess bjsm.bmj.com
✔️ 4. Plan ahead for travel
- West ≈ easier (delay your schedule)
- East ≈ harder (advance schedule)
- Control light exposure to shift your clock bjsm.bmj.com
Jet lag management is a competitive advantage.
🧠 Quick Glossary (Super Simple)
Executive function: Your brain’s CEO (planning, focus, decisions).
PVT: A reaction-time test; slower when sleep-deprived.
Glymphatic system: Your brain’s cleaning crew during deep sleep.
Sleep efficiency: How much of your time in bed is actually spent asleep.
References:
- Sen A, Tai XY. Sleep duration and executive function in adults. Curr Neurol Neurosci Rep. 2023;23:801–813. [link.springer.com]
- Nature Research Intelligence. Sleep deprivation and cognitive performance. Nature Portfolio. 2023. Available from: https://www.nature.com/… [nature.com]
- Skourti E, Simos P, Zampetakis A, et al. Long-term associations between objective sleep and verbal memory performance. Front Neurosci. 2023;17:1265016. [frontiersin.org]
- Hauglund NL, Andersen M, Tokarska K, et al. Norepinephrine‑mediated slow vasomotion drives glymphatic clearance during sleep. Cell. 2025;188(3):606‑622.e17. [cell.com]
- Shirolapov IV, Zakharov AV, Smirnova DA, et al. The role of the glymphatic clearance system in sleep–wake interactions and neurodegeneration. Neurosci Behav Physiol. 2024;54:199–204. [link.springer.com]
- Kong Y, Yu B, Guan G, et al. Effects of sleep deprivation on sports performance: a systematic review and meta-analysis. Front Physiol. 2025;16:1544286. [frontiersin.org]
- Gong M, Sun M, Sun Y, et al. Effects of acute sleep deprivation on sporting performance in athletes. Nat Sci Sleep. 2024;16:—. [tandfonline.com]
- Dean B, Hartmann T, Wingfield G, et al. Sleep restriction between consecutive days of exercise impairs cycling performance. J Sleep Res. 2023;32(3):e13857. [onlinelibr....wiley.com]
- Mah CD, Mah KE, Kezirian EJ, Dement WC. The effects of sleep extension on athletic performance in collegiate basketball players. Sleep. 2011;34(7):943–950. [psycnet.apa.org]
- Cunha LA, Costa JA, Marques EA, et al. Impact of sleep interventions on athletic performance: a systematic review. Sports Med Open. 2023;9:58. [link.springer.com]
- Teece AR, Beaven CM, Argus CK, et al. Daytime naps improve afternoon power and perceptual measures in elite rugby union athletes. Sleep. 2023;46(12):zsad133. [academic.oup.com]
- Mesas AE, Núñez de Arenas-Arroyo S, Martinez-Vizcaino V, et al. Daytime napping and cognitive/physical sport performance: meta-analysis of RCTs. Br J Sports Med. 2023;57(7):417–27. [bjsm.bmj.com]
- Haines Roberts SS, Teo WP, Warmington SA. Effects of training and competition on the sleep of elite athletes. Br J Sports Med. 2019;53(8):513–522. [bjsm.bmj.com]
- Walsh NP, Halson SL, Sargent C, et al. Sleep and the athlete: 2021 expert consensus recommendations. Br J Sports Med. 2021;55(7):356–368. [bjsm.bmj.com]
- Janse van Rensburg DC, Fowler PM, Racinais S. Practical tips to manage travel fatigue and jet lag in athletes. Br J Sports Med. 2021;55(15):821–822. [bjsm.bmj.com]
- Watson NF, Badr MS, Belenky G, et al. Recommended amount of sleep for a healthy adult: AASM/SRS consensus statement. Sleep. 2015;38(6):843–844. [aasm.org]
- Centers for Disease Control and Prevention. FastStats: Sleep in adults. CDC. 2024. Available from: https://www.cdc.gov/sleep/… [cdc.gov]
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ABOUT THE AUTHOR
Mohamad-Ali Salloum, PharmD
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Reference: ACRP. “ICH E6(R2) to ICH E6(R3) Comparison.” (Jan 28, 2025) — terminology & essential records: PDF Clinical Trials Toolkit. “Summary of Key Changes in ICH E6(R3).” (Mar 25, 2025) — proportionality, QbD, safety reporting: Article PharmaEduCenter. “Key changes between ICH GCP E6 R3 and E6 R2.” (Aug 10, 2025) — structure & glossary: Blog CITI Program. “Navigating the Transition from ICH E6(R2) to ICH E6(R3).” (Mar 12, 2025) — consent & site practices: Blog IntuitionLabs. “ICH E6 (R3) Explained.” (Updated Jan 13, 2026) — rationale, data governance: Deep dive
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